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Fully sequenced samples of complimentary DNA synthesized from single-stranded, mammalian RNA. Various gene inserts sourced from humans, mice, monkeys, and other species are available. Ideal for use in gene cloning, as gene probes, and in cDNA library creation.
The Fc gamma Rs have been divided into three classes based on close relationships in their extracellular domains these groups are designated Fc gamma RI (also known as CD64) Fc gamma RII (CD32) and Fc gamma RIII (CD16) Each group may be encoded by multiple genes and exist in different isoforms depending on species and cell type The CD64 proteins are high affinity receptors ( 10e-8-10e-9 M) capable of binding monomeric IgG whereas the CD16 and CD32 proteins bind IgG with lower affinities ( 10e-6-10e-7 M) only recognizing IgG aggregates surrounding multivalent antigens
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The immunoglobulin-like transcript (ILT) comprise a family of activating and inhibitory type immunoreceptors whose genes are located in the same locus that encodes killer cell Ig-like receptors (KIR) ILT4 also known as LIR-2 and LILRB2 is a type I transmembrane protein expressed primarily on monocytes and dendritic cells (DC) LILRB2 is a receptor for class I MHC antigens Recognizes a broad spectrum of HLA-A HLA-B HLA-C HLA-G and HLA-F alleles
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